Administration of annual oral high-dose vitamin D to community-dwelling older women in autumn and winter months increases risk of falls and fractures.
نویسنده
چکیده
Vitamin D defi ciency is an increasingly important worldwide issue. It is estimated that one billion people worldwide have vitamin D defi ciency or insuffi ciency.1 Vitamin D defi ciency has been linked to a multitude of problems across the lifespan. The importance of vitamin D and calcium absorption has been well documented. What remains unclear is the role of vitamin D in osteoporotic fracture prevention and specifi cally, the amount and regimen of vitamin D ingestion that is safe and effective in decreasing falls and subsequent fractures.
منابع مشابه
Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial.
CONTEXT Improving vitamin D status may be an important modifiable risk factor to reduce falls and fractures; however, adherence to daily supplementation is typically poor. OBJECTIVE To determine whether a single annual dose of 500,000 IU of cholecalciferol administered orally to older women in autumn or winter would improve adherence and reduce the risk of falls and fracture. DESIGN, SETTIN...
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UNLABELLED In this population-based study, seasonal periodicity was seen with reduced serum vitamin D, increased serum PTH, and increased bone resorption in winter. This was associated with an increased proportion of falls resulting in fracture and an increased risk of wrist and hip fractures. INTRODUCTION In a population of women who reside in a temperate climate and do not generally receive...
متن کاملKorean Society for Bone and Mineral Research Task Force Report: Perspectives on Intermittent High-dose Vitamin D Supplementation
An adequate supply of vitamin D is considered necessary for osteoporosis management and fracture prevention. Intermittent high-dose vitamin D supplementation is an effective and convenient way to achieve and maintain sufficient vitamin D status. However, the long-term effectiveness of supplementation for preventing falls and fractures is unclear, and some deleterious effects of such treatments ...
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ورودعنوان ژورنال:
- Evidence-based nursing
دوره 13 4 شماره
صفحات -
تاریخ انتشار 2010